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WHAT IS DOXORUBICIN?
Doxorubicin is a cancer medication that interferes with the growth and spread of cancer cells in the body. Doxorubicin is classified as an antitumor antibiotic. Antitumor antibiotics are made from natural products produced by species of the soil fungus Streptomyces. These drugs act during multiple phases of the cell cycle and are considered cell-cycle specific.
Doxorubicin Is Used For the various treatments like Acute lymphoblastic leukemia (ALL), Acute myeloblastic leukemia (AML), Bone sarcoma, Breast cancer, Endometrial cancer, Gastric cancer, Head and neck cancer, Hodgkin lymphoma, Non-Hodgkin lymphoma, Liver cancer, Kidney cancer, Multiple myeloma, Neuroblastoma, Ovarian cancer, Small Cell Lung cancer, Soft tissue sarcoma, Thyomas, Thyroid cancer, Transitional cell bladder cancer, Uterine sarcoma, Wilms’ tumor and Waldenström macroglobulinemia
POSSIBLE SIDE EFFECTS:
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.
Call your doctor at once if you have:
feeling short of breath (even with mild exertion), swelling, rapid weight gain; fever, chills, body aches, flu symptoms, sores in your mouth and throat; pale skin, easy bruising, unusual bleeding, feeling like you might pass out;
fast, slow, or uneven heartbeats; anxiety, sweating, severe shortness of breath, wheezing, gasping for breath;
chest pain, sudden cough, cough with foamy mucus, rapid breathing, coughing up blood; lower back pain, blood in your urine, little or no urinating;
numbness or tingly feeling around your mouth, weak pulse, overactive reflexes, confusion, fainting; muscle weakness, tightness, or contraction; or pain, burning, irritation, or skin changes where the injection was given.
Doxorubicin may cause your urine to turn a reddish-orange color. This side effect by itself is usually not harmful. However, call your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).
Common side effects may include:
missed menstrual periods; darkening of your skin or nails; temporary hair loss; feeling weak or tired; mild nausea, diarrhea; or eye redness, puffy eyelids.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Refrigerate unopened vials of Doxil at 2°– 8°C (36°– 46°F). Do not freeze.