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WHAT IS LAMIVUDINE/STAVUDINE/NEVIRAPINE?
Lamivudine belongs to a class of medication called nucleoside reverse transcriptase inhibitors. It decreases the amount of virus (HIV and hepatitis) in the blood. It also increases the number of infection fighting cells in the body (CD4 cells. Stavudine belongs to a group of drugs called as nucleoside reverse transcriptase inhibitors (NRTIs). It works by inhibiting multiplication of viruses thus decreasing their levels in the infected patient. Nevirapine belongs to a class of anti-HIV medicines called non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Lamivudine indicated as part of antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infected adults and children and also used in the treatment of Hepatitis B virus infection. Stavudine is used in combination with other anti-viral drugs in the treatment of Human Immunodeficiency Virus (HIV) infection. Nevarapine is used to treat and control Human Immunodeficiency Virus (HIV-1) infection for adults, adolescents, and children of any age. It must be used along with other HIV medicines.
POSSIBLE SIDE EFFECTS:
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some people develop lactic acidosis while taking lamivudine/Stavudine/ Nevirapine. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as:
muscle pain or weakness; numb or cold feeling in your arms and legs; trouble breathing; feeling dizzy, light-headed, tired, or very weak;
stomach pain, nausea with vomiting; or fast or uneven heart rate.
Call your doctor at once if you have:
pancreas problems--severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; or
liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
Common side effects may include:
diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; or abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Store at 20° to 25°C (68° to 77°F).