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WHAT IS EVEROLIMUS?
Everolimus is a targeted therapy and is classified as an mTOR inhibitor. Everolimus lowers your body's immune system. The immune system helps your body fight infections. The immune system can also fight or "reject" a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader.
Everolimus Is used For treatment of advanced renal cell cancer, after sunitinib and sorafenib treatment failure. Advanced pancreatic neuroendocrine tumors, treatment of advanced hormone receptor positive, HER2-negative breast cancer in post menopausal women, after letrozole or anastrozole treatment failure. Treatment of adult patients with certain types of neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin with unresectable, locally advanced or metastatic disease.
POSSIBLE SIDE EFFECTS:
EVEROLIMUS can cause a blood clot in the blood vessels of your transplanted organ, especially within 30 days after transplant. Tell your doctor right away if you have: shortness of breath, fever with nausea or vomiting, blood in your urine, dark colored urine, little or no urinating, jaundice (yellowing of your skin or eyes), or pain in your stomach, groin, lower back, or side.
Call your doctor at once if you have:
pain or burning when you urinate; redness, warmth, swelling, oozing, or slow healing of a wound or surgical incision; new or worsening cough, wheezing, breathing problems; stabbing chest pain, cough with yellow or green mucus;
pale skin, feeling light-headed, rapid heart rate, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum); white patches or sores inside your mouth or on your lips;
high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss); or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, uneven heartbeats, seizure).
Common side effects may include:
swelling in your legs, ankles, or feet; diarrhea, constipation; or mild stomach discomfort.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Tablets and tablets for suspension: Store at room temperature of 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light; protect from moisture.