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WHAT IS GEMCITABINE?
Gemcitabine is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Gemcitabine belongs to the family of drugs called antimetabolites. Antimetabolites are very similar to normal substances within the cell. When the cells incorporate these substances into the cellular metabolism, they are unable to divide. Antimetabolites are cell-cycle specific. They attack cells at very specific phases in the cycle.
Gemcitabine is used for pancreas cancer, non-small cell lung cancer, bladder cancer, soft-tissue sarcoma, metastatic breast cancer, ovarian cancer
POSSIBLE SIDE EFFECTS:
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. If you receive gemcitabine during or after radiation treatment, tell your doctor right away if you have severe skin redness, swelling, oozing, or peeling.
Also call your doctor at once if you have:
fever, chills, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums); blisters or ulcers in your mouth, red or swollen gums, trouble eating or swallowing; severe headache, blurred vision, buzzing in your ears, confusion, seizure (convulsions);
liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); signs of damaged red blood cells--bloody diarrhea, stomach pain with vomiting, blood in your urine, pale skin;
signs of a kidney problem--little or no urinating, painful or difficult urination, swelling in your feet or ankles; or
symptoms of a lung problem--sudden chest pain or discomfort, anxiety, sweating, severe shortness of breath, wheezing, gasping for breath, cough with foamy mucus, severe dizziness.
Common side effects may include:
nausea, vomiting; fever, unusual bleeding; abnormal blood or urine tests; trouble breathing; swelling in your hands or feet; mild rash; or red or pink urine.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Unopened vials of Gemcitabine for Injection are stable until the expiration date indicated on the package when stored at controlled room temperature 20° to 25°C (68° to 77°F) and that allows for excursions between 15° and 30°C (59° and 86°F)