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WHAT IS CARBOPLATIN ?
Carboplatin is an anticancer drug ("antineoplastic" or "cytotoxic") chemotherapy drug. Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. "Normal" cells stop dividing when they come into contact with like cells, a mechanism known as contact inhibition. Cancerous cells lose this ability. Cancer cells no longer have the normal checks and balances in place that control and limit cell division. The process of cell division, whether normal or cancerous cells, is through the cell cycle. The cell cycle goes from the resting phase, through active growing phases, and then to mitosis (division).
Carboplatin is used to treat ovarian cancer. Carboplatin is also used for other types of cancer, including lung, head and neck, endometrial, esophageal, bladder, breast, and cervical; central nervous system or germ cell tumors; osteogenic sarcoma; and as preparation for a stem cell or bone marrow transplant.
POSSIBLE SIDE EFFECTS:
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
fever, chills, body aches, flu symptoms, sores in your mouth and throat;
severe or ongoing vomiting; stomach pain, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); numbness or tingly feeling in your hands or feet; hearing or vision problems;
skin changes where the medicine was injected; or low magnesium (confusion, uneven heart rate, jerking muscle movements, muscle weakness or limp feeling).
Common side effects may include:
nausea, vomiting, loss of appetite; tired feeling; temporary hair loss; or pain, swelling or redness where the medicine was injected.
Unopened vials of Carboplatin Injection are stable for the life indicated on the package when stored at 25°C (77°F) [excursions permitted to 15°- 30°C (59°- 86°F) and protected from light. Carboplatin injection multidose vials maintain microbial, chemical, and physical stability for up to 15 days at 25°C following multiple needle entries.