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Composition : Nilotinib 200mg
Manufacturer : Novartis Pharma Stein AG
Packing : Pack of 28 Capsules
WHAT IS TASIGNA 200 MG ?
Nilotinib is a type of biological therapy called a protein tyrosine kinase inhibitor (TKI). Tyrosine kinases are proteins that act as chemical messengers (enzymes). They can stimulate cancer cells to grow. Nilotinib blocks a tyrosine kinase protein called Bcr-Abl. The protein is made by chronic myeloid leukaemia cells that have an abnormal chromosome called the Philadelphia chromosome. Blocking this protein stops the leukaemia cells growing. 95 out of 100 people with CML (95%) have the Philadelphia chromosome.
Nilotinib is used to treat a type of blood cancer called Philadelphia chromosome positive chronic myeloid leukemia (CML). Nilotinib is usually given after other medications have been tried without success.
POSSIBLE SIDE EFFECTS:
Get emergency medical help if you have any of these signs of an allergic reaction to Nilotinib: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using Nilotinib and call your doctor at once if you have:
swelling, rapid weight gain, feeling short of breath, bone marrow suppression--fever, chills, painful mouth sores, pale skin, easy bruising or bleeding, red or pink urine, bloody or tarry stools, cough, trouble breathing, feeling light-headed, rapid heart rate,
kidney problems--lower back pain, little or no urinating; pancreas problems--severe pain in your upper stomach spreading to your back, nausea and vomiting,
high or low potassium---confusion, slow or uneven heart rate, weak pulse, extreme thirst, increased urination, leg discomfort, tingly feeling, muscle weakness or limp feeling,
low calcium--numbness or tingly feeling around your mouth, fast or slow heart rate, muscle tightness or contraction, overactive reflexes,
low sodium--headache, confusion, slurred speech, hallucinations, vomiting, severe weakness, muscle cramps, loss of coordination, feeling unsteady, seizure (convulsions), shallow breathing;
liver problems--nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), or
bleeding in the brain--sudden headache, confusion, vision problems, and feeling like you might pass out.
Common Nilotinib side effects may include:
Diarrhea, constipation, stomach discomfort; mild itching or rash, temporary hair loss; runny or stuffy nose, sneezing, sore throat; mild headache, back pain, joint or muscle pain; or tired feeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Nilotinib capsules should be stored at 25°C (77°F); excursions permitted between 15° to 30°C (59° to 86°F)
Novartis Pharma Stein AG,
Schaffhausersstrasse, 4332, Stein, Switzerland
Novartis Healthcare Private Limited, Thane, India
MARKETED IN INDIA BY:
Novartis Healthcare Private Limited, Mumbai-400018, India