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WHAT IS LAMIVUDINE/TENOFOVIR DISOPROXIL FUMARATE?
Lamivudine belongs to a class of medication called nucleoside reverse transcriptase inhibitors. It decreases the amount of virus (HIV and hepatitis) in the blood. It also increases the number of infection fighting cells in the body (CD4 cells. Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs). Its structure closely resembles the natural structure of viral DNA, that helps it to incorporateitself into the viral DNA.
Lamivudine indicated as part of antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infected adults and children and also used in the treatment of Hepatitis B virus infection. Tenofovir is used in combination with other antiviral drugs in the treatment of human immunodeficiency virus (HIV) infections. It may also be used in very limited cases of long-term infections of liver caused by hepatitis B virus.
POSSIBLE SIDE EFFECTS:
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some people develop lactic acidosis while taking lamivudine/Tenofovir. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as:
muscle pain or weakness; numb or cold feeling in your arms and legs; trouble breathing; feeling dizzy, light-headed, tired, or very weak;
stomach pain, nausea with vomiting; or fast or uneven heart rate.
Call your doctor at once if you have:
pancreas problems--severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; or
liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
Common side effects may include:
diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; or abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Store at 20° to 25°C (68° to 77°F).