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Composition : Trastuzumab 440mg
Manufacturer : Emcure
Packing : Pack of 1 Vial with 858mg lyophilised powder and 1 vial with 20ml Solvent
WHAT IS TRASTUZUMAB?
Trastuzumab is a monoclonal antibody. Trastuzumab works by targeting the HER2/neu receptor on cancer cells. The HER2 gene produces a protein receptor on the cell surface that signals normal cell growth by telling the cell to divide and multiply. Some cancerous breast tissue has too much HER2 (HER2/neu overexpression), triggering the cells to divide and multiply very rapidly.
Trastuzumab is used to treat metastatic (spread) breast cancer. It is effective against tumors that overexpress the HER2/neu protein. As part of chemotherapy regimen for adjuvant treatment of lymph-node positive, HER2/neu protein positive breast cancer. Treatment of gastric (stomach) cancer. It is not known whether or not trastuzumab may be effective in other cancers that may also have this HER-2/neu protein, including ovarian, colon, endometrial, lung, bladder, prostate, and salivary gland tumors.
POSSIBLE SIDE EFFECTS:
Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, weak, short of breath, or if you have a headache, fever, chills, sudden chest pain, wheezing, dry cough, hives, or swelling of your face, lips, tongue, or throat.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
shortness of breath (even with mild exertion or while lying down); rapid or shallow breathing, grunting, gasping for breath, pain when you breathe; blue-colored skin or lips;
sudden chest pain or discomfort, wheezing, new or worsening cough; pounding heartbeats or fluttering in your chest; swelling, rapid weight gain;
fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms; or heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.
Common side effects may include:
nausea, diarrhea, weight loss; headache, sleep problems (insomnia), tiredness; mouth sores; fever, chills, cough, or other signs of infection; skin rash, bruising, pale skin; altered sense of taste; or cold symptoms such as stuffy nose, sinus pain, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Prior to reconstitution, store intact vials at 2°C to 8°C (36°F to 46°F). do not freeze.